subj
Art <-> Life
This is a steel and bronze sculpture of the Androgen Receptor (ligand binding domain) bound to enzalutamide, a drug that targets the protein and is used to treat prostate cancer. The sculpture was for Charles Sawyers at Memorial Sloan Kettering and was commissioned by Rodrigo Romero, a postdoctoral fellow in the lab.
The protein is made from polished steel. Enzalutamide was made from bronze and the base of the sculpture was made from steel and bronze. The stand is granite.
The protein is made from polished steel. Enzalutamide was made from bronze and the base of the sculpture was made from steel and bronze. The stand is granite.
subj
Impatience and progress
Jobs was impatient with anything less than perfection but at the same time spent years perfecting a single product. I've never understood this until now.
His impatience was never about outcomes, it was about inputs.
This explains why he couldn't tolerate mediocrity for a second, but he could wait years for excellence.
When you're impatient with outcomes, every day feels expensive. When you're impatient with inputs, every day feels like progress.
His impatience was never about outcomes, it was about inputs.
This explains why he couldn't tolerate mediocrity for a second, but he could wait years for excellence.
When you're impatient with outcomes, every day feels expensive. When you're impatient with inputs, every day feels like progress.
subj
Wholesome story, as the holidays near
She was 78, too poor for Christmas gifts, so she painted pictures instead.
Art critics rejected her as "amateur."
She became a millionaire anyway.
Eagle Bridge, New York, 1938. Anna Mary Robertson Moses was 78 years old and broke.
Seventy-eight years of hard labor. Raising ten children, Running a farm.
No art. No hobbies. No time for "creativity." Just survival.
Then Christmas came.
Anna wanted to give her children and grandchildren presents.
So she painted them pictures.
Because she was broke and needed something to give.
She used old boards and scraps of canvas. Cheap house paints.
She painted scenes she remembered: farms in winter, children sledding, sugaring-off parties, country fairs. Simple, colorful, naive paintings.
Her daughter suggested she try selling them at the local drugstore in Hoosick Falls.
The pharmacist agreed. He hung a few paintings in the window, priced between $3 and $5.
They sat there for months. Nobody bought them.
October 1938. A man walked past Thomas's Drug Store.
His name was Louis Caldor. He was an art collector from New York City.
He saw the paintings in the drugstore window and stopped.
They were... strange. Primitive. But there was something about them—a sincerity, a warmth, an authenticity that trained artists often lost.
Caldor bought every painting in the store.
Caldor drove back to New York City with a trunk full of paintings by an unknown 78-year-old farmwife.
For the next year, Caldor tried to get galleries interested.
They all said no.
"Too primitive." "Not real art."
The New York art world in 1939 was dominated by Abstract Expressionism, Surrealism, European modernism.
But Caldor didn't give up.
In October 1939, he convinced the Museum of Modern Art (MoMA) to include three of Anna's paintings in a group exhibition called "Contemporary Unknown American Painters."
Critics ignored Anna's work. But the public loved them.
.
November 1940. A breakthrough.
A prestigious New York gallery—Galerie St. Etienne—agreed to give Anna a solo exhibition. Her first.
The owner, Otto Kallir, titled the show: "What a Farm Wife Painted."
Anna Mary Moses became "Grandma Moses"—a marketing name that emphasized her age, her authenticity.
The exhibition was a sensation.
Not with art critics—But with regular people. Americans exhausted by the Depression and worried about World War II found comfort in Grandma Moses's paintings. They were happy. Nostalgic for a simpler America.
Paintings sold out. Newspapers wrote features. She was 80 years old.
For the next 21 years, she produced over 1,600 paintings between ages 78 and 101. Hundreds sold for thousands of dollars each.
She appeared on the cover of Time magazine (1953). She met President Harry Truman at the White House.
She became one of the most famous artists in America.
Art critics rejected her as "amateur."
She became a millionaire anyway.
Eagle Bridge, New York, 1938. Anna Mary Robertson Moses was 78 years old and broke.
Seventy-eight years of hard labor. Raising ten children, Running a farm.
No art. No hobbies. No time for "creativity." Just survival.
Then Christmas came.
Anna wanted to give her children and grandchildren presents.
So she painted them pictures.
Because she was broke and needed something to give.
She used old boards and scraps of canvas. Cheap house paints.
She painted scenes she remembered: farms in winter, children sledding, sugaring-off parties, country fairs. Simple, colorful, naive paintings.
Her daughter suggested she try selling them at the local drugstore in Hoosick Falls.
The pharmacist agreed. He hung a few paintings in the window, priced between $3 and $5.
They sat there for months. Nobody bought them.
October 1938. A man walked past Thomas's Drug Store.
His name was Louis Caldor. He was an art collector from New York City.
He saw the paintings in the drugstore window and stopped.
They were... strange. Primitive. But there was something about them—a sincerity, a warmth, an authenticity that trained artists often lost.
Caldor bought every painting in the store.
Caldor drove back to New York City with a trunk full of paintings by an unknown 78-year-old farmwife.
For the next year, Caldor tried to get galleries interested.
They all said no.
"Too primitive." "Not real art."
The New York art world in 1939 was dominated by Abstract Expressionism, Surrealism, European modernism.
But Caldor didn't give up.
In October 1939, he convinced the Museum of Modern Art (MoMA) to include three of Anna's paintings in a group exhibition called "Contemporary Unknown American Painters."
Critics ignored Anna's work. But the public loved them.
.
November 1940. A breakthrough.
A prestigious New York gallery—Galerie St. Etienne—agreed to give Anna a solo exhibition. Her first.
The owner, Otto Kallir, titled the show: "What a Farm Wife Painted."
Anna Mary Moses became "Grandma Moses"—a marketing name that emphasized her age, her authenticity.
The exhibition was a sensation.
Not with art critics—But with regular people. Americans exhausted by the Depression and worried about World War II found comfort in Grandma Moses's paintings. They were happy. Nostalgic for a simpler America.
Paintings sold out. Newspapers wrote features. She was 80 years old.
For the next 21 years, she produced over 1,600 paintings between ages 78 and 101. Hundreds sold for thousands of dollars each.
She appeared on the cover of Time magazine (1953). She met President Harry Truman at the White House.
She became one of the most famous artists in America.
subj
almost 200 year old tortoise. he's seen some things.
Meet Jonathan — The 191-Year-Old Tortoise! 🐢
https://astronomynews.site/?p=303
Jonathan, the Seychelles giant tortoise, just celebrated his 191st birthday, making him the oldest living land animal in the world! Born around 1832, Jonathan has witnessed centuries of history from Napoleon’s exile to modern-day inventions and has outlived generations of humans.
Though blind and without a sense of smell, he’s still full of life, enjoying hand-fed meals, socializing with fellow tortoises, and even maintaining a healthy love life!
https://astronomynews.site/?p=303
Jonathan, the Seychelles giant tortoise, just celebrated his 191st birthday, making him the oldest living land animal in the world! Born around 1832, Jonathan has witnessed centuries of history from Napoleon’s exile to modern-day inventions and has outlived generations of humans.
Though blind and without a sense of smell, he’s still full of life, enjoying hand-fed meals, socializing with fellow tortoises, and even maintaining a healthy love life!
express, not stress